The plane used semi-regularly in season 3 of the cult 80-90's action-adventure series MacGyver was reportedly destroyed in a tragic air crash while on a South American mission worthy of a MacGyver episode itself.
According to the Aviation Safety Network
the Douglas C-47A-90-DL plane, known by fans of the show as Jack Dalton's plane throughout the 3rd season, crashed into a mountain while on a flight to return Christian Agua Viva missionary group doctors back home from their relief work in Playa Grande on Nov 1, 1998.
The crash report states that the plane was flying through thick fog and rain, generated by tropical depression Mitch and was relying on instruments only when it crashed into the mountain killing 11 of it's 18 occupants. The plane was damaged beyond repair and subsequently written off.
There was apparently no flight plan filed.
The plane as it appeared in MacGyver