MacGyver’s home town in Minnesota. He returned here 3 times during the series, first as a stand-in coach for his old high school hockey team. He returned again on the anniversary of the shooting accident which killed his friend and a final visit to execute his Grandfather’s will.
Note: Mission City is a fictional town. As there were no references made to any near-by landmarks or locations which could be used to approximate a location we have no way of knowing where in Minnesota it is.